Proto-Oncogene Proteins c-ret

Receptor protein-tyrosine kinases involved in the signaling of GLIAL CELL-LINE DERIVED NEUROTROPHIC FACTOR ligands. They contain an extracellular cadherin domain and form a receptor complexes with GDNF RECEPTORS. Mutations in ret protein are responsible for HIRSCHSPRUNG DISEASE and MULTIPLE ENDOCRINE NEOPLASIA TYPE 2.

Also Known As:

Proto-Oncogene Protein Ret; Proto-Oncogene Protein c-ret; Receptor Tyrosine Kinase RET; Proto Oncogene Protein Ret; Proto Oncogene Protein c ret; Proto Oncogene Proteins c ret; Proto-Oncogene Proteins, ret; Ret, Proto-Oncogene Protein; c-ret, Proto-Oncogene Protein; c-ret, Proto-Oncogene Proteins; ret Proto Oncogene Proteins; c-ret Protein; ret Proto-Oncogene Proteins

Enzymes and Coenzymes: 1
- Enzymes: 155591
  - Transferases: 6719
    - Phosphotransferases: 43773
      - Phosphotransferases (Alcohol Group Acceptor)
        Protein Kinases: 9899
        Protein-Tyrosine Kinases: 7827
        Receptor Protein-Tyrosine Kinases: 6127
        Proto-Oncogene Proteins c-ret: 61
Carbohydrates: 22516
- Glycoconjugates: 1370
  - Glycoproteins: 25180
    - Membrane Glycoproteins: 2277
      - Cell Adhesion Molecules: 4912
        Cadherin Related Proteins: 1
        Proto-Oncogene Proteins c-ret: 61
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Glycoproteins: 25180
    - Membrane Glycoproteins: 2277
      - Cell Adhesion Molecules: 4912
        Cadherin Related Proteins: 1
        Proto-Oncogene Proteins c-ret: 61
  - Membrane Proteins: 10262
    - Cell Surface Receptors: 2156
      - Receptor Protein-Tyrosine Kinases: 6127
        Proto-Oncogene Proteins c-ret: 61
    - Cadherin Related Proteins: 1
      - Proto-Oncogene Proteins c-ret: 61
  - Intracellular Signaling Peptides and Proteins: 32
    - Protein-Tyrosine Kinases: 7827
      - Receptor Protein-Tyrosine Kinases: 6127
        Proto-Oncogene Proteins c-ret: 61
  - Neoplasm Proteins: 2
    - Oncogene Proteins: 7896
      - Proto-Oncogene Proteins: 7
        Proto-Oncogene Proteins c-ret: 61

M J Evinger Selected Research

M J Evinger Research Topics

Disease

Drug/Important Bio-Agent (IBA)